antiSMASH 5 feature list#
Rule-based detection of BGCs#
| BGC type |
|---|
| Aminocoumarins |
| Aminoglycosides / aminocyclitols |
| Aryl polyenes |
| atypical NRPS |
| atypical PKS |
| Bacteriocins |
| Beta-lactams |
| Beta-lactones |
| Bottromycin |
| Butyrolactones |
| ClusterFinder fatty acid |
| ClusterFinder Saccharide |
| Cyanobactins |
| Cyclodipeptide synthase-based tRNA dependent peptides |
| (Dialkyl)resorcinols |
| Ectoines |
| fungal RiPPs |
| Furan |
| Fused (Pheganomycin-like) |
| Glycocin |
| Head-to-tail cyclised peptide |
| Heterocyst glycolipid synthase like PKS |
| Homoserine lactone |
| Indoles |
| Ladderane lipids |
| Lanthipeptides |
| Lasso peptide |
| Linaridin |
| Linear azol(in)e-containing peptides (LAPs) |
| Lipolanthines |
| Melanins |
| Microviridin |
| N-acetylglutaminylglutamine amides |
| N-acyl amino acids |
| Non-ribosomal peptides |
| Nucleosides |
| Oligosaccharide |
| Others |
| Phenazine |
| Phosphoglycolipids |
| Phosphonate |
| Polybrominated diphenyl ethers |
| Polyunsaturated fatty acids |
| Proteusin |
| Pseudopyronines |
| RaS RiPPs |
| Sactipeptide |
| Siderophores |
| Terpene |
| Thiopeptide |
| Thioamide-containing non-ribosomal peptides |
| Trans-AT type I PKS |
| Type I PKS |
| Type II PKS |
| Type III PKS |
Rule-independent detection of BGCs#
Note: This function is only available in the download/locally run version
| Tool |
|---|
| ClusterFinder |
Region specific analyses#
| Analysis |
|---|
| Domain structure of PKSs and NRPSs |
| NRPS: A-domain specificity prediction (NRPSpredictor) |
| PKS: AT specificity prediction |
| Identification of conserved active site motifs; stereochemistry-determining motifs |
| Prediction of core chemical structure (NRPS, PKS, lanthipeptides, lasso peptides, thiopeptides) |
| smCOG secondary metabolism-related gene family prediction |
| TTA codon annotation for actinomycetes |
| Improved prediction of gene cluster borders for fungal BGCs (CASSIS) |
| Protein family detection (PFAM) search on regions |
| GO-classifications |
| Resistance gene annotation |
Genome-wide analyses#
| Analysis |
|---|
| Protein family detection (PFAM) search on whole genome |
| Genome comparisons |
| ClusterBlast (identification of similar clusters in sequence genomes); link to antiSMASH database |
| SubClusterBlast (identification of conserved operons with known function) |
| KnownClusterBlast (identification of similar characterized gene clusters) |
Links to other Web-resources#
| External resource |
|---|
| antiSMASH database |
| Gene ontology |
| MIBiG repository |
| NCBI BLAST+ |
| NaPDoS |
| Norine |
Output file formats#
| Format |
|---|
| Genbank |
| HTML |
| JSON results file |
Input file formats#
| Format |
|---|
| FASTA (nucleotide) |
| FASTA + GFF3 |
| Genbank |
| EMBL |
| Direct download via NCBI accession number |